The move is the result of a three-way collaboration between Aptar CSP, Uhlmann, and Ivers-Lee to expand the manufacturing of Activ-Blister technology globally


Aptar CSP Technologies announces a new manufacturing site for its Activ-Blister solutions for oral slide dose drugs in Europe. (Credit: AptarGroup, Inc.)

Aptar CSP Technologies has announced a new production site in Europe for its Activ-Blister solutions for oral slide dose drugs.

The move is the result of a three-way collaboration between Aptar CSP, Uhlmann, a pharmaceutical packaging equipment maker, and Ivers-Lee, a contract manufacturing organisation, to expand manufacturing of Activ-Blister technology globally.

Under the collaboration, Uhlmann provided a blister machine tested to package oral solid dosage medication products with Activ-Blister solutions heat-staked to the foil at a rate of up to 250 blisters per minute.

Aptar CSP, part of AptarGroup, said that the device is capable to put Activ-Blister technology within the blister cavity to deliver enhanced product stability and expedited speed-to-market for oral solid dose drugs.

Ivers-Lee, a CMO capable of manufacturing Activ-Blister solutions from R&D to commercialisation, has thoroughly verified the equipment and has it in place.

In EMEA, a CMO will help regional customers and ensure quick time to market.

Aptar CSP Technologies commercial operations VP Badre Hammond said: “Expanding global manufacturing sites for Activ-Blister technology reflects our commitment to delivering global access to innovative active material science solutions for patients and consumers.

“With manufacturing capabilities now available in both the US and EMEA, we will turn our attention to bringing production of this technology to the Asia market.”

Aptar CSP’s proprietary 3-Phase Activ-Polymer platform technology is compatible with specific blister cavities by Activ-Blister solutions for precise microclimate protection for delicate medicinal items.

The firm said that the technology can be customised to the drug developer’s formulation to provide a broad range of drug protection, such as moisture adsorption, oxygen and odour scavenging.

The technology can also scavenge and release volatile organic compounds (VOCs).

Last month, Aptar CSP Technologies expanded the production of its Activ-Vial system to China.